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Staresinic M, et al
Values were normalized to X-linked inhibitor of apoptosis protein (XIAP) to calculate relative enrichment as previously 38
Options include (a) the conservative 2.5 mg 5 mg path or (b) start at 5 mg if prior GLP-1 tolerance was excellent and the clinician prefers not to de-titrate. In either case, escalate by 2.5-mg increments no faster than every 4 weeks, pausing or stepping back if nausea, vomiting, or dehydration appear
Changes in blood flow: Medications that alter metabolic processes and blood flow could directly or indirectly affect clotting mechanisms
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